NFL Week 10 Showdown: Best Player Prop Bets for Commanders-Lions & 49ers-Rams

The late-afternoon slate for NFL Week 10 is packed with intrigue — and some juicy player prop opportunities. With matchups like Commanders vs. Lions and 49ers vs. Rams, bettors are watching closely to see which stars might light up the stat sheet.

In Detroit, Jared Goff and the Lions are looking to bounce back with a statement win. Expect Amon-Ra St. Brown to continue his high-volume dominance in the passing game, while Jahmyr Gibbs remains a dual-threat option both on the ground and through the air. If the Lions’ offensive line holds up, Gibbs could easily surpass his combined yards prop.

On the other side, Washington’s offensive weapons — especially Terry McLaurin — could find success against a Detroit defense that’s been inconsistent in coverage. With Jayden Daniels expected to lean on quick passes, short-yardage reception props might offer sneaky value.

Over in Los Angeles, Brock Purdy and the 49ers are eyeing redemption after a rocky stretch. Christian McCaffrey’s touchdown streak remains a near lock, but don’t overlook Brandon Aiyuk, who’s due for a breakout yardage performance. Meanwhile, the Rams’ Matthew Stafford is back, and Cooper Kupp looks ready to remind everyone why he’s one of the league’s best route runners.

Between these two matchups, there’s plenty of late-day action for fans and bettors alike. Whether you’re chasing yards, touchdowns, or receptions, Week 10’s late games promise fireworks — and maybe even a little extra money in your pocket.

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